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Regional prefrontal cortex gray matter reductions have been identified in schizophrenia, likely reflecting a combination of genetic vulnerability and disease effects. Few morphometric studies to date have examined regional prefrontal abnormalities in non-psychotic biological relatives who have not passed through the age range of peak risk for onset of psychosis. We conducted a region-of-interest morphometric study of prefrontal subregions in adolescent and young adult relatives of schizophrenia patients. Twenty-seven familial high-risk FHR first-degree relatives of schizophrenia patients and forty-eight control subjects without a family history of psychosis ages 13—28 underwent high-resolution magnetic resonance imaging at 1. The prefrontal cortex was parcellated into polar, dorsolateral, ventrolateral, ventromedial and orbital subregions. The Chapman scales measured subpsychotic symptoms.
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Higher Education Events Calendar & People

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Higher Education Events Calendar & People

Parnassus was the final film of the late Heath Ledger, who passed on before he had completed his scenes. Their show consists of a magic mirror which can transport those who step through it into a shifting, surreal wonderland created from their own imaginations, sometimes with terrifying results. The Doc claims to be centuries old, having gained immortality through a deal with The Devil, amusingly played by a relaxed, muttering Tom Waits. The story, which is somewhat confusingly explicated, also involves a character named Tony, played by Ledger, who falls in with the Imaginarium gang when they rescue him from an apparent suicide attempt.
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Edinburgh Napier University

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